We are currently offering two postdoctoral positions to undertake research on the molecular and cellular
mechanisms involved in muscle dystrophy caused by mutations in dysferlin. The project has an integrated view
of a health problem, and involves interaction with both clinicians and basic scientists. Successful candidates
must hold a PhD degree in the fields of biology or biomedicine, obtained within the last 4 years. Prior
knowledge of molecular and cellular biology of skeletal muscle cell is highly desirable, as well as an adequate
command of the English language. Good organizational and team work skills are also required.
The two positions entail work in the following areas:
1.‐ Role of dysferlin, and the impact of dysferlin mutations on DHP receptors and Ca2+ signaling (Drs. Caviedes,
Bevilacqua. Univ. of Chile)
The position requires expertise in cell culture, transfection techniques, immunoblotting, use of fluorophores to
study intracellular Ca2+ signaling, and patch clamp techniques.
2.‐ Role of dysferlin and/or dynamin‐2, and the impact of protein mutations, on cortical actin dynamics and
vesicle trafficking (Dr. Cárdenas, Univ. of Valparaíso).
The position requires expertise in cell culture, transfection techniques, and fluorescent microscopy techniques.
Expertise in TIRF microscopy is highly desirable.
The Salary range is $1.200.000 ‐ $1.400.000 Chilean pesos gross per month (Approximately, US$ 2500 – 2900;
1900 – 2200 €), commensurate with prior experience. The Rings Grant provides funding for up to 36 months.
Hiring will follow Conicyt regulations and Chilean labor laws.
mechanisms involved in muscle dystrophy caused by mutations in dysferlin. The project has an integrated view
of a health problem, and involves interaction with both clinicians and basic scientists. Successful candidates
must hold a PhD degree in the fields of biology or biomedicine, obtained within the last 4 years. Prior
knowledge of molecular and cellular biology of skeletal muscle cell is highly desirable, as well as an adequate
command of the English language. Good organizational and team work skills are also required.
The two positions entail work in the following areas:
1.‐ Role of dysferlin, and the impact of dysferlin mutations on DHP receptors and Ca2+ signaling (Drs. Caviedes,
Bevilacqua. Univ. of Chile)
The position requires expertise in cell culture, transfection techniques, immunoblotting, use of fluorophores to
study intracellular Ca2+ signaling, and patch clamp techniques.
2.‐ Role of dysferlin and/or dynamin‐2, and the impact of protein mutations, on cortical actin dynamics and
vesicle trafficking (Dr. Cárdenas, Univ. of Valparaíso).
The position requires expertise in cell culture, transfection techniques, and fluorescent microscopy techniques.
Expertise in TIRF microscopy is highly desirable.
The Salary range is $1.200.000 ‐ $1.400.000 Chilean pesos gross per month (Approximately, US$ 2500 – 2900;
1900 – 2200 €), commensurate with prior experience. The Rings Grant provides funding for up to 36 months.
Hiring will follow Conicyt regulations and Chilean labor laws.
Research Ring Grant # ACT 1211, Conicyt, Chile:
“Molecular and cellular mechanisms of muscular dystrophy related to mutations of dysferlin”
Pablo Caviedes (Director. ICBM, Faculty of Medicine, Univ. of Chile, Santiago, Chile)
Jorge Bevilacqua (Deputy Director. ICBM, Univ. of Chile Clinical Hospital, Santiago, Chile)
Ana María Cárdenas (CINV, Univ of Valparaíso, Valparaíso, Chile)
“Molecular and cellular mechanisms of muscular dystrophy related to mutations of dysferlin”
Pablo Caviedes (Director. ICBM, Faculty of Medicine, Univ. of Chile, Santiago, Chile)
Jorge Bevilacqua (Deputy Director. ICBM, Univ. of Chile Clinical Hospital, Santiago, Chile)
Ana María Cárdenas (CINV, Univ of Valparaíso, Valparaíso, Chile)
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